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INTRAORALLY DISINTEGRABLE TABLET COMPRISING DISINTEGRABLE GRANULAR COMPOSITION
专利权人:
DAICEL CORPORATION
发明人:
Takahiro HIRAMURA,Kiyoshi IKURA,Sae ITAYA,Tomohito OKABAYASHI,Anan SAKAGUCHI,Tetsuro MORITA,Kimiko IKEDA
申请号:
US14915872
公开号:
US20160213619A1
申请日:
2014.09.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
An object of the present invention is to provide an orally disintegrating tablet having both an excellent tablet hardness and disintegrability even when the content of a medicinal ingredient is high.This invention relates to an orally disintegrating tablet comprising a medicinal ingredient having distribution coefficient (log P) in a range of from −6.0 to 10.0 and a disintegrative particulate composition produced by granulation consisting of at least two stages, especially to said orally disintegrating tablet having tablet hardness of from 30 to 100 N, and disintegration time in water of from 10 to 30 sec.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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