NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

ZACHARY KELVIN SWEENEY,MICHAEL WELCH

申请号：

BRPI0809617

公开号：

BRPI0809617A2

申请日:

2008.03.18

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

Compounds of formula I, wherein R1, R2, R3, R4, R5, X, Y, and Ar are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.

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