Susan A. McDowell,Robert E. Sammelson,Larry A. Sklar,Mark K. Haynes
申请号:
US14561787
公开号:
US20150190408A1
申请日:
2014.12.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure relates to molecules which function as selective modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases and, in particular, CDC42 GTPase, and their use to treat bacterial infection including systemic infection from sources such as Staphylococcus aureus and Streptococcus pyogenes.