Complete human monoclonal IgG4lambda specific for CTLA-4 and uses thereof for detection of soluble CTLA-4 and isolation of regulatory cells

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专利权人:

Li-Te CHIN

发明人:

Li-Te CHIN,Shu-Ching Hsu

申请号：

US13107504

公开号：

US20120009207A1

申请日:

2011.05.13

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention provides a CTLA-4 non-blocking agent of a complete human antibody nature, thus is non-immunogenic in a human. The immunoassay method using such a non-blocking agent measures the CTLA-4 content in a sample of a human subject. The present invention further provides a novel method for isolating human regulatory T cells. The resultant enriched and depleted cellular populations are useful in treating or ameliorating of human diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/