CRYSTALLINE FORMS OF LORLATINIB MALEATE

• 收藏
• 分享

专利权人:

PFIZER INC.

发明人:

PENCHEVA, KLIMENTINA DIMITROVA

申请号：

CA3019905

公开号：

CA3019905A1

申请日:

2017.03.27

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

This invention relates to new crystalline forms of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3- h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile(lorlatinib) maleate. The invention also relates to pharmaceutical compositions comprising lorlatinib maleate, and to methods of using lorlatinib maleate and compositions comprising it in the treatment of abnormal cell growth, such as cancer,in mammals.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/