SEL DE MALEATE DE LA BASE LIBRE DE N- [5- (AMINOSULFONYL)-4-METHYL -1,3-THIAZOL-2-YL]-N-METHYL-2-[4- (2-PYRIDINYL)-PHENYL]-ACETAMIDE, FORMULATIONS PHARMACEUTIQUES, PROCEDES DE FABRICATION ET UTILISATIONS DE CEUX-CI POUR LE TRAITEMENT DU VIRUS DE L'HERPES
BACHHAV, YOGESHWAR,SCHWAB, WILFRIED,BIRKMANN, ALEXANDER,BONSMANN, SUSANNE,GOLDNER, THOMAS
申请号:
CA3045063
公开号:
CA3045063A1
申请日:
2017.11.28
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to the field of anti-viral active agents, particularly to salts, more particularly to a maleate salt of the free base of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2- yl]-N-methyl-2-[4-(2-pyridinyl)-phenyl]-acetamide, to pharmaceutical formulations thereof as well as to methods for the production of these salts. The present invention also relates to the use of theses salts and of respective pharmaceutical formulations thereof in methods of treatment and/or prevention of human herpes simplex virus infections, particulary infections caused by HSV-1 and HSV-2.