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Formulation comprising phenylaminopyrimidine derivative as active agent
专利权人:
NATCO PHARMA LIMITED
发明人:
PARVATANENI DURGA MAHESWARI,YEDLURI SIDDHARTHA,APPADWEDULA VENKATA SATYANARAYANA,ADIBHATLA KALI SATYA BHUJANGA RAO,NANNAPANENI VENKAIAH CHOWDARY
申请号:
NZ61490311
公开号:
NZ614903A
申请日:
2011.08.10
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is an oral pharmaceutical formulation comprising (3,5-bis-trifluoromethyl)-N-[4-methyl-3-({ 4-(pyridin-3-yl)-pyrimidin-2-yl} amino)-phenyl]-benzamide (also known as NRC-AN-019) including its pharmaceutically acceptable salts and polymorphs such as Form I, Form II and Form III, as well as a lipohilic phase, a surfactant and a water miscible solvent. The formulation is intended to improve the bioavailability of NRC-AN-019 upon contact with the gastro-intestinal fluid. Also disclosed is the use of the formulation containing NRC-AN-019 in the manufactureof a medicament for the treatment of chronic myeloid leukemia and against other tumors such as head and neck cancer and prostate cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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