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Systems and methods for polarized nuclear imaging and spectroscopy
专利权人:
University of Virginia Patent Foundation
发明人:
Cates, Gordon D.,Miller, G. Wilson,Zheng, Yuan,Tobias, William A.
申请号:
AU2015409278
公开号:
AU2015409278A1
申请日:
2015.10.01
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Some aspects of the present disclosure relate to systems and methods for examining a subject. In one embodiment, a method includes polarizing nuclei of a radioactive substance such that the spins of the nuclei are oriented in a specific direction, to generate a polarized radioactive tracer with anisotropic gamma ray emission probability. The method also includes introducing the tracer into a subject. The method further includes applying radio frequency oscillating (RF) magnetic fields and/or spatially varying magnetic fields to the tracer that are configured to manipulate the orientation of the spins such as to manipulate the directional dependence of gamma ray emission from the tracer. The method further includes detecting gamma rays from the gamma ray emission, and obtaining, based on the detected gamma rays and properties associated with the anisotropic gamma ray emission, imaging data and/or spectroscopic data associated with the tracer in the subject.
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