Vaccine compositions based on modified gp41 immunogens

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专利权人:

发明人:

申请号：

EP10382284.7

公开号：

EP2447277A1

申请日:

2010.10.28

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The invention relates to relates to human immunodeficiency virus (HIV) immunogens based on gp41 epitopes located in the membrane proximal extracellular region (MPER). The immunogens of the present invention are capable of inducing the expression of neutralizing antibodies. Various forms of these isolated immunogens are disclosed and exemplified. Isolated nucleic acid molecules expressing relevant portions of these immunogens, as well as the vectors and host cells utilized for their production, are also within the scope of the present invention.

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