Jankowski, Orion D.,Hinman, Andrew W.,Miller, Guy M.
申请号:
AU2011285619
公开号:
AU2011285619A1
申请日:
2011.08.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Methods of treating, preventing or suppressing symptoms associated with mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), dominant optic atrophy (DOA); mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), Leigh syndrome or Kearns-Sayre Syndrome (KSS) with compounds of Formula (I) are disclosed. Methods of modulating, normalizing, or enhancing energy biomarkers, as well as compounds useful for such methods are also disclosed.