Methods and compositions for enhancing delivery of double-stranded RNA or a double-stranded hybrid nucleic acid to regulate gene expression in mammalian cells
Mohammad Ahmadian,Kunyuan Cui,Lishan Chen,Shu-Chih Chen,Michael E. Houston, Jr.
申请号:
US12870989
公开号:
US08940857B2
申请日:
2010.08.30
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A delivery-enhancing peptide comprising the amino acid sequence of SEQ ID NO:11 or salt thereof. This invention is directed towards methods and compositions to administer a double-stranded ribonucleic acid to a mammal so as to effectuate transfection of the double-stranded RNA into a desired tissue of the mammal.