A method of directing positioning of ECG electrodes on a patient includes receiving at a processor an image of a patient from a camera of an augmented reality device. The processor analyzes the image for anatomical landmarks on the patient and generates an overlay image. The overlay image is shown over the real time image of the patient on the augmented reality device. The overlay image includes visual indicators of the desired electrode placement. The method further includes determining whether the actual location of each of the electrodes is correct and provides information on the augmented reality device as to whether the electrodes and lead placement is correct. An image of the electrode placement is stored with the ECG measurements, which can be used to verify correct electrode placement and to confirm consistent electrode placement over serial measurements. The augmented reality device allows for gesture control by the clinician.