Piercing one or more containers (e.g., single use containers) within a cleaning and disinfecting device is provided. An actuator (e.g., motor, or the like) causes drive mechanisms to move a member (e.g., tube) and/or a piercer linearly with respect to a longitudinal axis of the member. The actuator moves the member towards a container until the piercer has pierced a portion of the container. A guide may form a seal with a reservoir located under the container to create a seal with the reservoir and keep contents of the container from passing from a reservoir to components of a piercer apparatus. Alternatively, the piercer and/or guide form a seal with the container, and the contents pass from the container to an outlet channel in the member, such that the contents of the container are emptied out of the container to the outlet channel and directly or indirectly to a medical device.