Sanford Burnham Prebys Medical Discovery Institute
发明人:
Anthony B. PINKERTON,Robert J. ARDECKY,Jiwen ZOU
申请号：
US16610055
公开号：
US20200055875A1
申请日:
2018.04.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Protein tyrosine phosphatases (PTPs) are key regulators of metabolism and insulin signaling. As a negative regulator of insulin signaling, the low molecular weight protein tyrosine phosphatase (LMPTP) is a target for insulin resistance and related conditions. Described herein are compounds capable of modulating the level of activity of low molecular weight protein tyrosine phosphatase (LMPTP) and compositions, and methods of using these compounds and compositions.
