Disclosed herein are core-shell particles and process for preparing the same. The core-shell particles include a functional core, a multilayer or porous shell surrounding the functional core and polymeric tails extending from the shell. The functional core includes an antimicrobial agent or an antitumor agent. Also disclosed herein are pharmaceutical or health care compositions containing the core-shell particles.本揭示內容為殼核粒子及製備殼核粒子的方法。殼核粒子包含一功能性核心、一圍繞該功能性核心的多層或多孔性殼、以及多條由該多層或多孔性殼表面往外延伸出來的聚合鏈。該功能性核心包含一抗微生物劑或一抗腫瘤劑。本揭示內容亦提供一種包含該殼核粒子的醫藥或口腔保健組合物。
