Described herein are chlorite formulations having a pH between about 7 and about8.5, wherein the chlorite formulations are substantially free of deleteriousnon-chlorite components. Described herein are chlorite formulations, includingpharmaceutical formulations, which are formulated for systemic, parenteral,or intravenous administration. Described herein are methods of preparing andmethods of using the chlorite formulations described herein.