Robert Kisilevsky,Shui-Pang Tam,John B. Ancsin,Zongchao Jia
申请号：
US12701709
公开号：
US08703698B2
申请日:
2010.02.08
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
