A therapeutic protocol to induce placenta cell death when required in the treatment of an adverse gynecological condition is applicable, inter alia, to the treatment of ectopic pregnancy, including unruptured ectopic pregnancy and placenta tumors, such as a hydatidiform molar pregnancy or choriocarcinoma. The protocol includes administering vinorelbine or a pharmacologically active and pharmaceutically acceptable salt, solvate, tautomer, stereoisomer, derivative, biosimilar or prodrug form of vinorelbin in an amount effective to induce placenta cell death