A manipulator system includes: a manipulator including an elongated flexible section, a movable section provided at a distal end of the flexible section, and a driver that is provided at a proximal end of the flexible section and that drives the movable section; an insertion section having a channel into which the manipulator is inserted; an advancing/retreating section that advances/retreats the manipulator and that causes the movable section of the manipulator to protrude from, and to be withdrawn into, a distal end of the channel; a protrusion-state acknowledgement section that acknowledges a protrusion state in which an entirety of the movable section protrudes from the distal end of the channel; and a restricting section that, when the protrusion state is acknowledged with the protrusion-state acknowledgement section, restricts further retreating motion of the driver performed by the advancing/retreating section.