BRET SELLMAN,LEI HUANG,PARTHA S. CHOWDHURY,CHRISTINE TKACZYK,PETER PAVLIK,REBECCA BUONPANE,CHEW-SHUN CHANG
申请号：
MX2015005477
公开号：
MX2015005477A
申请日:
2013.11.06
申请国别(地区):
MX
年份:
2015
代理人:
摘要：
Antibodies and antigen binding fragments directed against Staphylococcus aureus (S. aureus) surface determinant antigens and bi- specific antibodies comprising the antibodies or binding fragments that also bind to secreted toxins are disclosed. Methods of detecting, diagnosing and treating S. aureus infection using the antibodies and antigen binding fragments are also provided. Further disclosed are heavy chain variable region (VH) and light chain variable region (VL) region sequences of the antibodies.Se describen anticuerpos y fragmentos de unión al antígeno de estos dirigidos contra determinantes antigénicos de la superficie Staphylococcus aureus (S. aureus) y toxinas secretadas. También se proporcionan métodos para detectar, diagnosticar y tratar S. aureus empleando los anticuerpos y fragmentos de unión al antígeno de estos.
