ZLOKARNIK, GREGOR,YANG, XIAOQING,GROOTENHUIS, PETER, D
申请号:
NZ59515110
公开号:
NZ595151A
申请日:
2010.03.19
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
ABSTRACT - 595151 Disclosed is a compound of formula (I) which are modulators of cystic fibrosis transmembrane conductance regulator ("CFTR"), wherein R is COOH or CH2OH. These compounds are particularly suitable for treating disease selected from cystic fibrosis, smoke induced COPD, pancreatitis, pancreatic insufficiency, hereditary emphysema, COPD, and dry-eye disease.