A method of treating a pathologic legion, such as an intravascular thrombus, is disclosed. The method comprises providing a guide wire and catheter with at least one inductive element within a blood vessel to a distal location associated with the pathologic lesion and providing electromagnetic energy via at least one inductive element to the pathologic lesion to cause thrombolysis. Medicated magnetic particles can be endovascularly localized and concentrated to the vascular territory affected by the pathologic lesion.
