Prevent retinal disease enough [challenges] practical, mucosal application agents which can be treated or improved, in particular, to provide an effective eye drops for the disease of the posterior segment of the eye. Treatment for mucosal application agents prevention of retinal diseases, including [MEANS FOR SOLVING PROBLEMS] geranylgeranylacetone, or improved. Suitable retinal disease is such as diabetic retinopathy glaucoma, retinitis pigmentosa, and age-related macular degeneration,. [Selection] Figure Figure 1【課題】実用上十分に網膜疾患を予防、改善、又は治療できる粘膜適用剤、特に、後眼部の疾患に対して有効な点眼剤を提供する。【解決手段】ゲラニルゲラニルアセトンを含む網膜疾患の予防、改善、又は治療用粘膜適用剤。好適な網膜疾患は、緑内障、網膜色素変性、加齢黄斑変性、及び糖尿病性網膜症などである。【選択図】図1