To provide a laminate tablet capable of suppressing generation of a carbon dioxide gas over time and suppressing expansion of a package in a pharmaceutical preparation, a pharmaceutical preparation and a production method of a laminate tablet.SOLUTION: The laminate tablet comprises an α layer including the following (A) component and substantially not including the following (B) component, and a β layer including the (B) component and substantially not including the (A) component, and includes (C) component in one or both of the α layer and β layer. The (A) component is one or more kinds selected from acetylsalicylic acid and salt thereof, the (B) component is a magnesium-based antacid, the (C) component is one kind or more kinds selected from lactose hydrate, lactose granulated object, saccharose, partially pregelatinized starch, potato starch, pregelatinized starch, carboxymethyl starch, carboxymethyl starch sodium, carboxymethyl cellulose, carboxymethyl cellulose calcium, hydroxymethyl cellulose and mannitol.SELECTED DRAWING: None【課題】経時に伴う炭酸ガス等の発生が抑えられて医薬製剤における包装体の膨張を抑制できる積層錠、医薬製剤及び積層錠の製造方法。【解決手段】下記（Ａ）成分を含有し、下記（Ｂ）成分を実質的に含有しないα層と、下記（Ｂ）成分を含有し、下記（Ａ）成分を実質的に含有しないβ層と、を有し、前記α層及び前記β層の一方又は双方に下記（Ｃ）成分を含有する、積層錠。（Ａ）成分：アセチルサリチル酸及びその塩から選択される１種以上。（Ｂ）成分：マグネシウム系制酸剤。（Ｃ）成分：乳糖水和物、乳糖造粒物、ショ糖、部分α化デンプン、バレイショデンプン、α化デンプン、カルボキシメチルスターチ、カルボキシメチルスターチナトリウム、カルボキシメチルセルロース、カルボキシメチルセルロースカルシウム、ヒドロキシメチルセルロース及びマンニトールから選択される１種以上。【選択図】なし
