KORYTKO, ANDREW IHOR,MARQUIS, DAVID MATTHEW,SMITH, ERIC MICHAEL,SWANSON, BARBARA ANNE
申请号：
CA2682212
公开号：
CA2682212C
申请日:
2008.03.11
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
