REMODELAGE ET GLYCOPEGYLATION DU FACTEUR DE CROISSANCE DES FIBROBLASTES (FGF)

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专利权人:

INC.;NEOSE TECHNOLOGIES

发明人:

DEFREES, SHAWN

申请号：

CA2585758

公开号：

CA2585758C

申请日:

2005.10.31

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention relates to mutants of Fibroblast Growth Factor (FGF),particularly FGF-20 and FGF-2 1, which contain newly introduced N-linked or O-linked glycosylation site(s). The polynucleotide coding sequences for themutants, expression cassettes comprising the coding sequences, cellsexpressing the mutants, and methods for producing the mutants are alsodisclosed. Further disclosed are pharmaceutical compositions comprising themutants and method for using the mutants.

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