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Multilayer Biodegradable Microparticles for Sustained Release of Therapeutic Agents
专利权人:
LLC;Ohr Pharma
发明人:
Chris Rhodes,Robert Jennings,Nikita Malavia,Laxma Reddy,Norman Betty
申请号:
US15687366
公开号:
US20170354611A1
申请日:
2017.08.25
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Microparticles are prepared by a method that includes: (a) forming a layer comprising a first polymer on a solid surface by depositing a first composition one or more times on the solid surface, wherein the first composition comprises the first polymer and a first solvent, and evaporating the first solvent in the first composition; (b) forming one or more layers comprising a second polymer and a therapeutic agent by depositing a second composition on all or part of the layer formed in step (a), wherein the second composition comprises the second polymer, the therapeutic agent, and a second solvent; and evaporating the second solvent in the second composition; and (c) forming an additional layer comprising a third polymer by depositing a third composition one or more times on a previously formed layer, wherein the third composition comprises the third polymer and a third solvent; and evaporating the third solvent in the third composition.
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中国工程科技知识中心
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