COMPOSITIONS AND METHODS OF USE FOR (PRO)RENIN RECEPTOR ANTAGONISTS

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专利权人:

University of Utah Research Foundation

发明人:

Yumei Feng Earley,Tianxin Yang

申请号：

US15501159

公开号：

US20180125922A1

申请日:

2015.07.31

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Disclosed are methods of treating kidney disease, infectious or inflammatory diseases, acute kidney injury and hypertension by administering a (pro)renin receptor (PRR) antagonist. In some instances the PRR antagonist is a polypeptide. The PRR antagonist can be a polypeptide having at least 70% identity to the amino acid sequence set forth in SEQ ID NO:2. Also disclosed are methods of decreasing proteinuria and methods of promoting wound healing by administering a PRR antagonist.

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