Jason Imbriglio,Clare London,Zhijian Lu,James Tata,Yusheng Xiong,Ming You,Hyewon Youm
申请号：
US15508557
公开号：
US09877957B2
申请日:
2015.08.31
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a compound represented by formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I are inhibitors of diacylglyceride O-acyltransferase 2 (“DGAT2”) and may be useful in the treatment, prevention and suppression of diseases mediated by DGAT2. The compounds of the present invention may be useful in the treatment of hepatic steatosis, diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cardio renal diseases such as chronic kidney diseases and heart failure and related diseases and conditions.
