Bok Luel Lee,Kurokawa Kenji,Dong-Jun Jung,Jang-Hyun An,Yu-Jin Jeon,Na Hyang Kim,Takahashi Kazue,Eunmi Kim,Dong Ho Ahn
申请号:
US14399225
公开号:
US20150147328A1
申请日:
2013.05.07
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a vaccine composition for preventing staphylococcus aureus infection containing, as an active ingredient, a ribitol-phosphate which has been modified only by a β-configuration in N-Acetylglucosamine (GlcNAc), a repeating unit of the ribitol-phosphate, or a wall teichoic acid (WTA) containing the repeating unit. The composition according to the present invention contains a coupling motif (an epitope) for an anti-WTA antibody, and thus can be effectively used as a vaccine composition or to prevent staphylococcus aureus infection by generating anti-WTA antibody.