The present invention relates to an assembled T-cell receptor (TCR) comprising at least one of the following amino acid residues, wherein the amino acid residue is selected from the group consisting of the L96 residue of the? R9 residue of alpha chain； Y10 residue of alpha chain； the T24 residue of the alpha chain； the V19 residue of the alpha chain； the T20 residue of the alpha chain； the M50 residue of the alpha chain； the T5 residue of the alpha chain； Q8 residue of alpha chain； S86 residue of alpha chain； F39 residue of alpha chain； D55 residue of alpha chain； the R43 residue of the? chain； A66 residue of alpha chain； the V19 residue of the alpha chain； L21 residue of alpha chain； L103 residue of alpha chain； the T3 residue of the alpha chain； S7 residue of alpha chain； P9 residue of alpha chain； M11 residue of alpha chain； the A16 residue of the alpha chain； T18 residue of alpha chain； L21 residue of alpha chain； S22 residue of alpha chain； D26 residue of alpha chain； the F40 residue of the alpha chain； S47 residue of alpha chain； the R48 residue of the alpha chain； Q49 residue of alpha chain； I51 residue of alpha chain； L52 residue of alpha chain； the V53 residue of the alpha chain； the T67 residue of the alpha chain； E68 residue of alpha chain； the N74 residue of the alpha chain； the F76 residue of the alpha chain； N79 residues in the alpha chain； Q81 residue of alpha chain； A83 residue of the alpha chain； K90 residue of alpha chain； the S92 residue of the alpha chain； D93 residue of alpha chain； And the M101 residue of the [alpha] -chain, and wherein at least one of the amino acid residues is absent in the corresponding germline TCR amino acid sequence.본 발명은 적어도 하나의 하기 아미노산 잔기를 포함하는 조립된 T-세포 수용체(TCR)에 있어서, 아미노산 잔기는 α사슬의 L96 잔기； α 사슬의 R9 잔기； α 사슬의 Y10 잔기； α사슬의 T24 잔기； α사슬의 V19 잔기； α사슬의 T20 잔기； α사슬의 M50 잔기； α사슬의 T5 잔기； α사슬의 Q8 잔기； α사슬의 S86 잔기； α사슬의 F39 잔기； α사슬의 D55 잔기； α 사슬의 R43 잔기； α사슬의 A66 잔기； α 사슬의 V19 잔기； α 사슬의 L21 잔기； α 사슬의 L103 잔기； α사슬의 T3 잔기； α사슬의 S7 잔기
