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THERAPY FOR MALIGNANT DISEASE
专利权人:
发明人:
Richard G. MOORE,Rakesh K. SINGH,Naohiro YANO
申请号:
US15561466
公开号:
US20180117075A1
申请日:
2016.03.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein, inter alia, are methods and compositions directed to suppressing tumor cell growth in a subject as well as methods for sensitizing a proliferating cell for treatment with a cytotoxic agent via inhibiting expression of HE4 and one or more immune checkpoint inhibitors (ICIs). Also provided herein are methods for determining whether a subject who has been diagnosed with cancer would benefit from immunotherapy as well as methods for determining whether a subject with cancer is responding to immunotherapy via assessment of levels of HE4 gene and/or protein expression.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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