PROBLEM TO BE SOLVED: To provide a method for producing a silk fiber three-dimensional structure in a biologically safe process, using silk protein of high biocompatibility, which can be used in the fields of regenerative medicines and perfume cosmetics and the like.SOLUTION: A silk fiber three-dimensional structure is produced by using silk protein aqueous solution with a concentration of 4w/v% or more and 22 w/v% or less and a pH of 8-12 as spinning solution, according to electric field spinning.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2018,JPO&INPIT【課題】再生医療や香粧分野等において利用ができる、生体親和性の高いシルクタンパク質を用いて、生体に対して安全なプロセスでシルク繊維立体構造体を製造する方法の提供。【解決手段】電界紡糸法に従って、紡糸液として、濃度が4w/v%以上22w/v%以下であり、pHが8~12であるシルクタンパク質水溶液を用い、シルク繊維立体構造体を製造する。【選択図】図1
