WOLFGANG GLAESNER,ROHN LEE MILLICAN JUNIOR,ANDREW MARK VICK,LIANSHAN ZHANG,JOHN PHILIP MAYER
申请号：
IN4284/KOLNP/2007
公开号：
IN256041B
申请日:
2007.11.07
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The invention provides GLP-1 compounds coupled to two polyethylene glycol molecule or derivative thereof, resulting in a biologically active peptide with an extended half-life and a slower clearance when compared to that of unPEGylated peptide. These PEGylated GLP-1 compounds and compositions are useful in treating conditions or disorders benefited by lowering blood glucose, decreasing food intake, decreasing gastric or intestinal emptying, increasing beta (ß) cell population, or decreasing gastric or intestinal motility.
