OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY
发明人:
CHOUTHAIWALE, PANDURANG V.,TANAKA, FUJIE
申请号:
EP13845790
公开号:
EP2885282A4
申请日:
2013.10.10
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Disclosed is a process for preparing dihydro-2H-pyran derivatives of formula I: wherein R1 and R2 are defined herein. The process of the invention provides the compound of formula I in concise cascade reactions and in one pot. The compound of formulae I prepared by the process of the invention and its further transformed derivatives are useful for making pharmaceutical composition for the treatment of proliferative diseases.