METHODE ET COMPOSITION POUR TRAITER L'HYPER-EXCITABILITE NEURONALE

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专利权人:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人:

MARSALA, MARTIN

申请号：

CA3018960

公开号：

CA3018960A1

申请日:

2017.03.27

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention provides a therapy for treating loss of GABA-mediated pre-synaptic inhibition after spinal injury. The therapeutic regimen includes spinal segment-specific upregulation of GAD65 (glutamate decarboxylase) and VGAT (vesicular GABA transporter) to modulate chronic spasticity in patients after spinal traumatic or ischemic injury.

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中国工程科技知识中心

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http://www.ckcest.cn/home/