NOUVEL ADJUVANT DE SAPONINE ET SON PROCEDE D'EVALUATION

• 收藏
• 分享

专利权人:

OBI PHARMA INC.

发明人:

YU, CHENG-DER, TONY,HSIEH, YIH-HUANG,LEE, WEI, HAN,LIN, YU, CHEN,WANG, NAN, HSUAN

申请号：

CA3095340

公开号：

CA3095340A1

申请日:

2019.03.27

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present disclosure is related to the six isomer structures (OBI-821-1990-V1A, OBI-821-1990-V1B, OBI-821-1990-V2A, OBI-821-1990-V2B, OBI-821-1858-A, and OBI-821-1858-B) of isolated OBI-821 adjuvant and the method for evaluating the quality thereof. The method of the present disclosure adopts hydrophilic interaction liquid chromatography (HILIC) and reverse phase high performance liquid chromatography (RP-HPLC) either alone or in tandem and is able to separate the isomers of OBI-821 adjuvant in the consequent chromatography. Accordingly, the quality of OBI-821 adjuvant can be further evaluated.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/