IRBM - Science Park S.p.A.;C.N.C.C.S. Scarl Collezione Nazionale Dei Composti Chimici e Centro Screening
发明人:
申请号：
EP13785845.2
公开号：
EP2914589B1
申请日:
2013.10.30
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention relates to compounds useful for treating parasitic diseases, which are infectious diseases caused or transmitted by a parasite. Compounds of the invention are particularly active against the causative pathogens in malaria. Such compounds are selective inhibitors of parasitic histone deacetylase (PfHDAC) and suppress the growth of parasites, such as Plasmodium falciparum, at a lower concentration than the concentration required for the inhibition of the growth of mammalian cells.
