PREVENTION AND TREATMENT OF ALZHEIMERS DISEASE BY GENOME EDITING USING THE CRISPR/CAS SYSTEM

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专利权人:

发明人:

申请号：

EP15789631.7

公开号：

EP3140403A4

申请日:

2015.05.08

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Methods and products related to genome editing using the CRISPR/Cas9 system to introduce an A673T substitution into an APP gene, such as guide RNAs and recombinant proteins, are described for decreasing APP levels produced by a cell, and use for the treatment of Alzheimers disease and/or age-related cognitive decline in a cell from a subject in need thereof.

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中国工程科技知识中心

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http://www.ckcest.cn/home/