The invention relates to a polymeric, non-coding nucleic acid molecule for modulation of the activity of the human and animal immune system as well as method for the manufacture thereof and a vaccine, comprising the polymeric, non-coding nucleic acid molecule, wherein polymeric, non-coding nucleic acid molecules may be understood as non-coding nucleic acid molecules, comprising at least four covalently bound molecules (tetramer) or are assemblies of more non-coding nucleic acid molecules (high molecular polymers) which are covalently bound to each other.本發明涉及一種調節人類和動物免疫系統活性之聚合的、非編碼核酸分子,和其生成方法,以及一種包括聚合的、非編碼核酸分子的疫苗,其中聚合的、非編碼核酸分子可理解為非編碼核酸分子,包括至少四個共價鍵結分子(四聚體)或由更多彼此共價鍵結的非編碼核酸分子(高分子聚合體)組成。
