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Device with nanocomposite coating for controlled drug release
专利权人:
Cook Medical Technologies LLC
发明人:
Ruane, Patrick
申请号:
AU2007212697
公开号:
AU2007212697B2
申请日:
2007.01.26
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
An implantable medical device including a nanocomposite coating depositedon at least a portion of a surface to provide a controlled release of a bioactiveagent in one or more dosages is described. The nanocomposite coating includesa matrix, a bioactive agent and inorganic particles. The inorganic particlesrespond to a stimulus, preferably by generating heat. The response of the particlesto the stimulus causes the matrix of the nanocomposite coating to undergo a volumechange by, for example, contracting or swelling, thereby releasing at leasta portion of the bioactive agent. A method of providing a controlled release ofa bioactive agent from a nanocomposite coating on an implantable medical deviceis described. A method for preparing an implantable medical device coated witha nanocomposite coating for the controlled release of a bioactive agent is alsodescribed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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