PROBLEM TO BE SOLVED: To provide a clip device of a biological tissue, a clip device having excellent operability in which a ratchet comes to function only in protruding operation of a clip clamping ring, thereby facilitating clip protruding operation in a short time with accuracy.SOLUTION: The clip device of a biological tissue is equipped with an operation part for operating a clip position for an introducing tube. The operation part includes: a first slider installed in the introducing tube a second slider that is capable of to-and-fro movement relative to the first slider and that operates the clip position a locking member installed in one of the first slider and the second slider and a plurality of locking receiving parts that are installed in the other of the first slider and the second slider, that are alternately arranged along the to-and-fro direction, and that determine the region where the locking member does not engage and the position relative to the introducing tube of the clip which is used where the locking member is functional and because the locking member functions.
