It refers to an anti OX40 antibody, including VH chains with three SEQ ID CDR numbers 101, 102 and 103; and VL chains with three CDRs with SEQ ID numbers 104, 105 and 106. He also mentioned a nucleic acid, a vector, a bone cell, a pharmacological compound, including these antibodies and methods for processing, as well as the treatment of bladder cancer, breast cancer, gastric cancer, etc.Referido a un anticuerpo anti-OX40 que comprende una cadena VH que comprende tres CDR de SEQ ID NOs: 101, 102 y 103; y una cadena VL que comprende tres CDR de SEQ ID NOs: 104, 105 y 106. Tambien se refiere a un acido nucleico, un vector, una celula huesped, una composicion farmaceutica incluyen dichos anticuerpos y metodos para su elaboracion; ademas de uso para tratar el cancer de vejiga, mama, gastrico, entre otros.