ДОЛТОН Джеймс Т. (US),МИЛЛЕР Дуэйн Д. (US),ЛИ Чиэнь-Мин (US),АН Суньцзо (US),ЛУ Янь (US),ВАН Чжао (US),ЧЭНЬ Цзяньцзунь (US),ЛИ Вэй (US),ДЬЮК Чарльз (US)
申请号：
RU2013112871/04
公开号：
RU2013112871A
申请日:
2011.08.24
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A compound represented by the structure of formula XI:, wherein X is NH or S Q is O, NH or S and A is a substituted or unsubstituted, mono-, or fused multi-ring, aryl or (hetero) cyclic ring systems substituted or unsubstituted, saturated or unsaturated N-heterocycles substituted or unsubstituted, saturated or unsaturated S-heterocycles substituted or unsubstituted, saturated or unsaturated O-heterocycles substituted or unsubstituted, saturated or unsaturated cyclic hydrocarbons or a substituted or unsubstituted, or saturated or unsaturated mixed heterocycle wherein said ring A is optionally substituted with 1-5 substituents which independently are O-alkyl, O-haloalkyl, F, Cl, Br, I, haloalkyl, CF, CN, -CHCN , NH, hydroxy, - (CH) NHCH, - (CH) NH, - (CH) N (CH), -OC (O) CF, C-Clineynym or branched alkyl, haloalkyl, alkylamino, aminoalkyl, -OCHPh, - NHCO-alkyl, COOH, -C (O) Ph, C (O) O-alkyl, C (O) H, -C (O) NHili NO ANDi is an integer of from 0 to 5.2. A compound according to claim 1, wherein said compound represented by the structure of formula VIII: R, r and are independently hydrogen, O-alkyl, O-haloalkyl, F, Cl, Br, I, haloalkyl, CF, CN, -CHCN, NH, hydroxyl, - (CH) NHCH, - (CH) NH, - (CH) N (CH), -OC (O) CF, C-Clineynym or branched alkyl, haloalkyl, alkylamino, aminoalkyl, -OCHPh, -NHCO-alkyl, COOH , -C (O) Ph, C (O) O-alkyl, C (O) H, -C (O) NHili NO Q is S, O or NH i is an integer from 0 to 5 and n is an integer of from 1 to 3.3. A compound according to claim 1, wherein said compound represented by the structure of formula XI (c) :, wherein R independently are hydrogen, O-alkyl, O-haloalkyl, F, Cl, Br, I, haloalkyl, CF, CN, -CHCN, NH , hydroxy, - (CH) NHCH,1. Соединение, представленное структурой формулы XI:,где Х является NH или SQ является О, NH или S иА является замещенными или незамещенными одно-, конденсированными или многокольцевыми, арильными или (гетеро)циклическими кольцевыми системами замещенными или незамещенными, насыщенными или ненасыщенными N-ге
