FORMULATIONS TAMPONNEES D'EXENDINE (9-39)

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专利权人:

EIGER BIOPHARMACEUTICALS;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY; INC.;EIGER BIOPHARMACEUTICALS, INC.

发明人:

XIONG, XIAOFENG,ODINK, DEBRA,CRAIG, COLLEEN M.,SMITH, CHRISTINE M.N.

申请号：

CA3043899

公开号：

CA3043899A1

申请日:

2017.11.21

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Provided herein are liquid pharmaceutical formulations comprising exendin (9-39) or a pharmaceutically acceptable salt thereof and a tonicity modifier in a physiologically acceptable buffer having a pH in the range of about 5 to about 6. In some embodiments, the liquid pharmaceutical formulation comprises exendin (9-39) or a pharmaceutically acceptable salt thereof in an acetate buffer or a citrate buffer. Methods of treating or preventing hyperinsulinemic hypoglycemia in a subject comprising administering to the subject the liquid pharmaceutical formulation are also provided.

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