PANDEY, RAVINDRA K.,BAUMANN, HEINZ,GURU, KHURSHID,CHERUKI, RAVINDRA,TRACY, ERIN,DURRANI, FARUKH,CACACCIO, JOSEPH,SITERS, KEVIN
申请号:
CA3047105
公开号:
CA3047105A1
申请日:
2017.12.13
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Compounds including a tetrapyrrolic or reduced tetrapyrrolic group/moiety and an epidermal growth factor receptor targeting group are disclosed. For example, a compound includes a tetrapyrrolic or reduced tetrapyrrolic group or moiety, a linker moiety, an epidermal growth factor receptor targeting group, and, optionally, a PET-active functional group. Uses of the compounds, for example, methods of treating a hyperproliferative tissue in an individual, and kits including one or more of the compounds are also provided.