GERHARD MUHRER,THOMAS KIECKBUSCH,DILRAJ SINGH,RANJIT THAKUR,KURT SCHAFFLEUTZEL,NORBERT RASENACK
申请号:
BRPI0820745
公开号:
BRPI0820745A2
申请日:
2008.12.11
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
A process of preparing a particulate and substantially crystalline drug substance. The process involves suspending a substantially crystalline drug substance in an anti-solvent to give a suspension, homogenising the suspension at elevated pressure to give drug particles that have a mean particle size of less than about 10 μm, and drying the drug particles to remove any residual anti-solvent.