Compacted gastro resistant Pharmaceutical composition comprising one or more Enzymes autoesambladas, where the Enzymes retain at least 30% of its activity after Exposure to gastric Fluid for 1 hour at 37； Preparation Process； and their use in partial exocrine pancreatic insufficiency Or complete, cystic fibrosis, among others
MATEESCU MIRCEA ALEXANDRU,BUSTOS INGRY JANET,DUMOULIN YVES,SZABO POMPILIA ISPAS
申请号：
CL2012002605
公开号：
CL2012002605A1
申请日:
2012.09.20
申请国别(地区):
CL
年份:
2013
代理人:
摘要：
The present invention generally relates to compacted pharmaceutical compositions (such as tablets) comprising one or more enzymes, where the composition is monolithic or multiparticulates (such as mini-tablets, micro-tablets, or prills), or where the composition has multiple layers with the outermost layer containing one or more enzymes.COMPOSICIÓN FARMACEUTICA COMPACTADA GASTRO-RESISTENTE QUE COMPRENDE 1 O MAS ENZIMAS AUTOENSAMBLADAS, DONDE LAS ENZIMAS RETIENEN AL MENOS 30% DE SU ACTIVIDAD DESPUÉS DE LA EXPOSICION A FLUIDO GASTRICO POR 1 HORA A 37°C； PROCESO DE PREPARACION； Y SU USO EN INSUFICIENCIA PANCREATICA EXOCRINA PARCIAL O COMPLETA, FIBROSIS QUISTICA, ENTRE OTRAS.
