CYCLIC PYRIMIDIN-4-CARBOXAMIDES AS CCR2 RECEPTOR ANTAGONISTS FOR TREATMENT OF INFLAMMATION, ASTHMA AND COPD

• 收藏
• 分享

专利权人:

发明人:

申请号：

HK14110176.9

公开号：

HK1197748A

申请日:

2011.12.15

申请国别(地区):

HK

年份:

2015

代理人:

摘要：

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD. Formula (I), wherein A is selected from among a single bond, =CH-, -CH2-, -O-, -S-, and -NH- wherein n is 1, 2 or 3 wherein Z is C or N, the other variables are as defined in the claims, as well as in form of their acid addition salts with pharmacologically acceptable acids.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/