To provide a method for functionally transplanting exocrine cell into a mammalian subject.SOLUTION: A method for transplanting exocrine cell into a mammalian subject, comprises: (1) a step of transplanting an exocrine cell into the submucosal layer of digestive tract of mammalian subject； (2) a step of removing the proper mucosal layer and mucosal muscle plate at the transplant site； and (3) a step of regenerating only the proper mucosal layer at the removal site.SELECTED DRAWING: Figure 1A【課題】哺乳類被験体へ外分泌細胞を機能的に移植する方法を提供する。【解決手段】哺乳類被験体へ外分泌細胞を移植する方法であって、（１）外分泌細胞を、哺乳類被験体の消化管の粘膜下層中に移植する工程、（２）移植部位の固有粘膜層及び粘膜筋板を除去する工程、及び（３）除去部位で固有粘膜層のみを再生させる工程を含む方法。【選択図】図１Ａ
